Dr R K Sanghavi

  # RKS: HIGH LDL! ... ALWAYS STATINS??  DISSECTING LDL AS NEVER BEFORE RKS / 2024-2025 / Ser 5 / Blog 4 1st August 2024 WHY sdLDL MOST ATHEROGENIC? A GUIDANCE FOR GUIDING THE GUIDES Dear Reader, The 'bad' cholesterol (C) is the low density lipoprotein (LDL) particles floating in the blood. This is more than a well-known fact and details relevant to this have been elaborated in the September 1, 2023 blog titled: # RKS: THE 'BAD' CHOLESTEROL - Is All LDL-Cholesterol Dangerous? Going one step further, how does the LDL-C subtype levels influence the need for statins. This is indeed a tricky question and the same could even be countered by the medical professionals from their over-concerned dyslipidemic (suffering from abnormalities in lipid profile) patients. LININGS OF BODY There are two linings for the body: EPITHELIUM: The coverings of body that are exposed to outside environment such as respiratory and digestive systems have  linings called epithelia. ENDOTHELIUM: Thes

  # RKS: IS BEING FAIR ... REALLY LOVELY TONE OR TANNING? (II) RKS / 2024-2025 / Ser 5 / Blog 3 1st July 2024                                              DISSECTING FAIRNESS CREAMS THE DAWN OF SKIN BRIGHTENING CREAMS ERA Dear Reader, Tanning is essentially the skin's response to increased melanin production after exposure to sunlight, creating a darkening effect. Skin tone, on the other hand, is the surface skin color which is determined by a dynamic genetic mechanism. Fig:  World regions and distribution of skin tone. Since South-east Asia and Africa host significant clusters of people with a darker skin hue, the population of these countries always desire for a fairer skin so as to be able to integrate better with the rest of the world where towards all the migration occurs. The surge in the Indian cosmetic market size of USD 8 bn (₹ ~64,000 crore) is mainly accounted by products that intend to modify skin tone. The global cosmetic market is USD 375 bn but India’s share is mere

  # RKS: IS BEING FAIR ... REALLY LOVELY TANNING OR TONE? (I) RKS / 2024-2025 / Ser 5 / Blog 2 1st June 2024                                              DISSECTING FAIRNESS CREAMS SKIN TANNING & COMBATING Dear Reader, The global ‘fairness’ products market is valued at USD 10 billion (₹ ~80,000 crore). The market in India is estimated to be worth nearly ₹ 5,000-10,000 crore and the average growth rate in the last two decades has been a healthy (sic) 20%. It is not only the Indians who are fanatic for looking ‘fairer’, the people of Nigeria and Ghana rule in this regard. This is evident from the list of top 5 countries whose population are frequent users of various fairness-related skin products globally. Table: Country populace opting for skin color reducing by using various available agents - top 5 countries. Although fairness of skin is most sought after by the Asians and Africans, the whole world clamours for products which are for either: (a) skin lightening; (b) skin whitening