Dr R K Sanghavi

   # RKS: GHRELIN = OBESITY  THE NUTRACEUTICAL COCKTAIL TO REDUCE GHRELIN 1st November 2023 REVISITING GHRELIN REDUCING GHRELIN = REDUCING CALORIE INTAKE = REDUCING WEIGHT Dear Reader, The name “ghrelin” is derived from “ghre” which means grow and “relin” which means release. Ghrelin is a hormone produced by ghrelinergic cells located in stomach. These cells have a direct communication channel open with brain. Hence, even when one does not intend to consume food, ghrelin can message the brain to increase appetite and thereby facilitate eating and drinking. The weight of an individual is decided by the balance between ghrelin and leptin hormones. Leptin, made by the fat cells in the buttocks, belly paunch and other ‘ballooned’ portions in those overweight and obese, decreases appetite. Ghrelin, on the other hand, makes one to eat food because of its appetite-stimulating action.  If one needs to keep the weight in check, especially those overweight desiring reducing th...

  # RKS: HORMONES & OBESITY  THE LITTLE KNOWN LINK 1st October 2023 GHRELIN - THE SAGA & ENIGMA EXPLORING OBESITY HORMONES MODULATING POSSIBILITIES Dear Reader, Ghrelin stimulates the brain, which leads to an increase in appetite, and it slows metabolism and decreases the body's ability to burn fat. Ghrelin also favors the amassing of fatty tissue in the abdominal area. Hence, Ghrelin is a do-all hormone as far as obesity is concerned. If Ghrelin is this the key hormone playing a role in obesity it could make fascinating reading about the same since globesity is the current most prevalent scourge of mankind. ALL ABOUT GHRELIN Ghrelin is produced by the stomach and is famously known as the ‘hunger hormone’. It is a multifaceted hormone since, besides stimulating food intake, Ghrelin participates in many other functions which directly or indirectly contribute to obesity. Fig: Ghrelin actions. It is well-documented that Ghrelin is an orexigenic hormone – i.e. it facilitat...